Retatrutide: Triple-Action Medication Transforming Weight Loss and Metabolism
Retatrutide may be the most potent weight-loss and metabolic medication to date. Unlike older GLP-1 drugs that target one or two pathways, retatrutide activates three: GLP-1, GIP, and glucagon.
GLP-1 reduces hunger and slows gastric emptying. GIP enhances how the body processes glucose and fats. Glucagon promotes the use of stored fat for energy. By engaging all three pathways, retatrutide can support faster, more efficient weight loss and improved metabolism.
Early research also indicates potential benefits beyond weight loss, including better cardiovascular markers, reduced inflammation, and improved insulin sensitivity—even in people without diabetes.
A deeper review of potential side effects and precautions will follow.